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Drug ReportsMetamizole sodium
Dipyrone
Dipyrone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
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Variants
Financial
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N02: Analgesics
— N02B: Other analgesics and antipyretics in atc
— N02BB: Pyrazolones, analgesics and antipyretics
— N02BB02: Metamizole sodium
— N02BB52: Metamizole sodium, combinations excl. psycholeptics
— N02BB72: Metamizole sodium, combinations with psycholeptics
HCPCS
No data
Clinical
Clinical Trials
55 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postoperative painD010149—G89.18—124815
PainD010146EFO_0003843R52—1—236
PancreatitisD010195EFO_0000278K85———123
Ischemic strokeD000083242—————112
StrokeD020521EFO_0000712I63.9———112
AnesthesiaD000758—————112
Acute painD059787—R52———112
Aortic aneurysmD001014EFO_0001666I71.9———112
Chronic painD059350————11—2
Cytomegalovirus infectionsD003586EFO_0001062B25———1—1
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Migraine disordersD008881EFO_0003821G43——1——1
HeadacheD006261—R51——1——1
Wounds and injuriesD014947—T14.8——1——1
Spinal cord injuriesD013119EFO_1001919———1——1
NeuralgiaD009437EFO_0009430———1——1
MyocarditisD009205—I51.4——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Covid-19D000086382—U07.1—1———1
Respiratory distress syndromeD012128EFO_1000637J80—1———1
Acute lung injuryD055371EFO_0004610——1———1
Newborn respiratory distress syndromeD012127—P22—1———1
SyndromeD013577———1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Drug interactionsD004347——2————2
Enzyme inductionD004790——1————1
Healthy volunteers/patients———1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Gingival recessionD005889—K06.0————55
Postoperative nausea and vomitingD020250EFO_0004888—————44
VomitingD014839—R11.1————44
AnalgesiaD000698——————33
Tooth abrasionD014072—K03.1————33
NauseaD009325—R11.0————22
Vitreoretinal surgeryD057586——————22
Tick-borne encephalitisD004675EFO_1001309A84————22
EncephalitisD004660——————22
MeningitisD008581EFO_0000584G03————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDipyrone
INN_
Description
Metamizole sodium is an organic sodium salt of antipyrine substituted at C-4 by a methyl(sulfonatomethyl)amino group, commonly used as a powerful analgesic and antipyretic. It has a role as a non-narcotic analgesic, an antirheumatic drug, a peripheral nervous system drug, an antipyretic, a prodrug, a cyclooxygenase 3 inhibitor and an anti-inflammatory agent. It contains a metamizole(1-).
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
Cc1c(N(C)CS(=O)(=O)[O-])c(=O)n(-c2ccccc2)n1C.O.[Na+]
Identifiers
PDB—
CAS-ID68-89-3
RxCUI1537943
ChEMBL IDCHEMBL3989803
ChEBI ID—
PubChem CID522325
DrugBankDB04817
UNII ID6429L0L52Y (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,778 adverse events reported
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